Uruguay is next with 28 and is widely expected to qualify.
Current form does not bode at all well, with Argentina failing to win any of their last four games and not winning a qualifier away from home since March 2016, when they triumphed 2-1 in Chile. So, it comes as no surprise that, with Argentina's World Cup hopes hanging in the balance, and Brazil having a say in their destiny, Seleçao fans are calling for action. The only way for Uruguay to fall to fifth is: it loses to Bolivia, plus Chile, Colombia and Argentina all win and Argentina scores at least nine goals to overtake Uruguay on goal difference. Iceland (19) sits pretty on the top but Croatia (17) is second on goal difference with Ukraine closing on. It's not gonna happen - Luis Suarez is going to the World Cup. No change to the table - Chile still in 5th. While the Seleção have nothing to play for, they sent out a quality team to play Bolivia on Thursday (though they promptly drew 0-0). A win will guarantee the visitors a ticket to Russian Federation, while any other result will leave them sweating on events elsewhere.
Pre-match: Right, so this could get complicated. If those two teams draw, then other results come into play.
And if that won't solve it, get set for the drawing of lots.
Ecuador were without Manchester United's Antonio Valencia and Michael Arroyo through suspension following last week's 2-1 loss in Chile. Turkey is out of contention after it lost against Iceland 3-0 on Friday, but many nations have everything to play for in their last games.
In a match that encapsulates all the rising tension of the last few matchdays, fourth-placed Colombia, who have 26 points to their name, travel to fifth-placed Peru, who lie a point behind them.
Colombia gets an automatic berth with a victory at Peru regardless of other results.
Of course, Argentina - who are now 6th and outside the playoff spot - will be praying Brazil can do them a massive favour.
Jose Paolo Guerrero scored a 76th-minute equaliser for Peru against Colombia, and they will face New Zealand in a two-legged play-off next month.
They are two of British football's most decorated players, but neither was ever able to demonstrate their considerable talents at a World Cup as Wales and Northern Ireland respectively failed to ever make a major tournament during their illustrious careers.
Colombia hasn't lost a World Cup qualifier in Peru since 1981 and if they can avoid defeat on Tuesday they'll likely be headed to Russian Federation. Los Cafeteros have since recorded four wins and three draws on Peruvian soil.
Argentina could qualify if it defeats Ecuador, which is already disqualified.